Benadryl side effects long term - Benadryl may cause serious side effects including: pounding heartbeats or fluttering in your chest, painful or difficult urination, little or no urination, confusion, lightheadedness, tightness in your neck or jaw, and. uncontrollable movements of your tongue. Get medical help right away, if you have any of the symptoms listed above.

 
Benadryl dosage for dogs. The correct dosage of diphenhydramine for dogs depends on their weight. A small dog will need much less than a big dog to receive the same positive effects. According to .... Fx

Jul 5, 2023 · Benadryl is an antihistamine that can be used to treat allergic reactions, relieve motion sickness, as a sleep aid, and relieve some symptoms of Parkinson's disease. Sedation is a common side effect. 5. Tips. Benadryl may be taken with or without food. Take exactly as directed. Long term use of some antihistamines may increase your risk of dementia. Diphenhydramine (Benadryl®) blocks the effects of a neurotransmitter called acetylcholine. This neurotransmitter is vital for memory and learning. Diphenhydramine increased the risk of dementia by 54% in one 3,000 patient study followed for seven years. IV administration of 50 mg of DPH resulted in immediate improvement of tremor, rigidity, tachycardia, and eye versions. The patient was started on oral DPH 50 mg 4 times a day and the dose was reduced by 25% every 3 days. Oral clonidine 0.1 mg 3 times a day and a weekly 0.1 mg transdermal patch was added to mitigate sympathetic side effects.Answer (1 of 2): Here is one long term study: “These drugs are called anticholinergics, among them the first-generation antihistamines that are now marketed as sleep aids.Long-term use may also lead to harmful side effects. The inability to fall or stay asleep can have a significant, negative impact on your mood, productivity, and overall health. Insomnia can also ...Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Not able to pass urine or change in how much urine is passed. A very bad skin reaction ( Stevens-Johnson syndrome / toxic epidermal necrolysis) may happen.Oct 3, 2022 · Some dosage forms listed on this page may not apply to the brand name Benadryl Allergy. Summary. More frequent side effects include: sedated state and thickening of bronchial secretions. Continue reading for a comprehensive list of adverse effects. Applies to diphenhydramine: oral capsules and tablets, parenteral injection. Side effects include: Jul 7, 2022 · Advertisement constipation. blurred vision. memory problems and dementia (especially in seniors) anxiety. dependence. What are the side effects of taking Benadryl every night? SIDE EFFECTS: Drowsiness, dizziness, constipation, stomach upset, blurred vision, or dry mouth/nose/throat may occur. If any of these effects persist or worsen, tell your doctor or pharmacistRead More → Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold.These symptoms include rash, itching, watery eyes, itchy eyes/nose/throat, cough, runny nose ... Apr 24, 2023 · Long-term use may also lead to harmful side effects. The inability to fall or stay asleep can have a significant, negative impact on your mood, productivity, and overall health. Insomnia can also ... Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold.These symptoms include rash, itching, watery eyes, itchy eyes/nose/throat, cough, runny nose ... Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold.These symptoms include rash, itching, watery eyes, itchy eyes/nose/throat, cough, runny nose ... The main long-term side effects of Plaquenil are eye-related. ... To manage your symptoms, they may suggest an over-the-counter antihistamine you take by mouth, such as Benadryl (diphenhydramine ...A 2017 study revealed that 10% of adults aged 18-45 use OTC sleep aids while 17.5% of people 65 years and older do. Most over-the-counter options are considered safe when used occasionally—as long as the medication is compatible with any medical conditions you have and other medications you take. But when taken night after night, trouble can ...Long-term side effects Over-the-counter Benadryl is approved for temporary or short-term use and is not intended for long-term use. There is very little scientific research about the long-term ...When corrected based on the number of drugs with anticholinergic effects an individual was taking, the odds ratio for cognitive impairment was 1.46 with a p value of .0181. However, overall the authors conclude that their data did not support the hypothesis that the use of anticholinergic medications increased the risk of alzheimer’s dementia ...Yes, certain side effects are possible after using Benadryl long term. For example, long-term use of Benadryl may cause: an increased risk of dementia; withdrawal symptoms after the drug is stopped* However, keep in mind that doctors typically don’t recommend taking Benadryl as a long-term treatment.The Major Antihistamine Effects of Diphenhydramine Prevents Histamine-Mediated: constriction of respiratory smooth muscle. rapid vasodilation in blood vessels. increased capillary permeability and subsequent edema. sensations of itching, pain, and “flare” formation. increase in heart rate and strength of contraction.Besides having side effects including drowsiness, confusion, and urinary retention, a new study shows that frequent, long-term use of older antihistamines are associated with an increased risk of ...Long-term side effects Over-the-counter Benadryl is approved for temporary or short-term use and is not intended for long-term use. There is very little scientific research about the long-term ...Yeah, look at r/dph.Datura is even worse. It's like dph, but way more likely to kill you or make you go blind. Shadow people and spiders and having full conversations with people who don't exist usually only happens in the 400+ category. Between 150mg and there, it's usually just having to piss but being unable to, dysphoria/fear, be The main long-term side effects of Plaquenil are eye-related. ... To manage your symptoms, they may suggest an over-the-counter antihistamine you take by mouth, such as Benadryl (diphenhydramine ...The symptoms you have noticed are very likely the result of long-term heavy antihistamine use. Antihistamines tend to dry up the nose, which is why they are so effective in humans with allergic rhinitis, but the way they do that is by making the secretions thicker. In dogs, we are not worried much about a runny nose, but we are concerned about ...Mar 21, 2023 · There is very little scientific research about the long-term effects of Benadryl. Some side effects that may occur with long-term use include: constipation; blurred vision When corrected based on the number of drugs with anticholinergic effects an individual was taking, the odds ratio for cognitive impairment was 1.46 with a p value of .0181. However, overall the authors conclude that their data did not support the hypothesis that the use of anticholinergic medications increased the risk of alzheimer’s dementia ...There is evidence that the use of diphenhydramine among older adults or the elderly may result in serious side effects. This holds true esp. if you are older than age 65. The older a person becomes, the greater the risk of adverse effects. Benadryl is listed as potentially Inappropriate Medication in Older Adults ( also known as Beers criteria)“Atarax (hydroxyzine) and Benadryl (diphenhydramine) were routinely administered in the chemotherapy I received for breast cancer. After 5 months of chemo, I attributed my loss of mental function to a condition I read about called “chemo brain” — and chalked it up as another price paid in side affects for the benefit of staying alive.Yes, certain side effects may be possible with long-term use of Benadryl. However, doctors usually don’t recommend Benadryl for long-term use. Instead, they typically advise short-term use of the drug to ease certain symptoms. The drug’s label information* for Benadryl does not specify any long-term side effects for this drug.May 8, 2019 · Answer. While Benadryl ( diphenhydramine) can safely be used once in a while as a sleep aid, long-term use is not recommended for multiple reasons. Even the intermittent use of Benadryl for sleep isn't generally recommended if you are elderly (over 65). Studies show that the elderly population doesn't metabolize Benadryl as quickly and are far ... Dizziness Nausea or vomiting Loss of appetite Constipation Increased chest congestion Headache Excitability (especially in children) Nervousness Benadryl can impair mental and motor functioning, as well as your performance at work or school. It can also impair a person’s ability to operate a motor vehicle or other potentially dangerous equipment.Diphenhydramine, brand name Benadryl ®, is one of the oldest and most frequently used over-the-counter medications for children. However, many better options are now widely available, all of which are faster acting, longer lasting, with less side effects. Antihistamines counteract the effect of histamine throughout the body, and treat a range ...Nov 15, 2019 · Central side effects. Since these actions are disrupted by sedating antihistamines, these drugs produce sedation, drowsiness, tiredness, lack of concentration, difficulty in learning and memory ... and readily penetrates the blood-brain-barrier. Thus side effects such as grogginess, drowsiness, and memory loss are common. Diphenhydramine is also used for motion sickness and extrapyramidal symptoms in Parkinson’s disease patients. Potential harm to the brain: Long-term anticholinergic use has been associated with increasedPotential Kidney Risks. Yes, long-term use of Benadryl can put strain on the kidneys, as it can build up in the system. This can cause toxicity and potentially lead to kidney damage. It's important to be aware of the potential side effects of long-term use and to consult a doctor if any symptoms arise.Diphenhydramine, which is available as an over-the-counter medication, is a first-generation antihistamine that is used in a variety of conditions to treat and prevent dystonias, insomnia, pruritis, urticaria, vertigo, and motion sickness. It also possesses local anesthetic properties for those patients who have allergies to other, more commonly used local anesthetics; however, this is an off ...May 19, 2022 · Yes, certain side effects are possible after using Benadryl long term. For example, long-term use of Benadryl may cause: an increased risk of dementia; withdrawal symptoms after the drug is stopped* However, keep in mind that doctors typically don’t recommend taking Benadryl as a long-term treatment. Oct 3, 2022 · Applies to diphenhydramine: oral capsules and tablets, parenteral injection. Side effects include: Sedation, sleepiness, dizziness, disturbed coordination, epigastric distress, thickening of bronchial secretions. May 22, 2013 · When corrected based on the number of drugs with anticholinergic effects an individual was taking, the odds ratio for cognitive impairment was 1.46 with a p value of .0181. However, overall the authors conclude that their data did not support the hypothesis that the use of anticholinergic medications increased the risk of alzheimer’s dementia ... Long term use of some antihistamines may increase your risk of dementia. Diphenhydramine (Benadryl®) blocks the effects of a neurotransmitter called acetylcholine. This neurotransmitter is vital for memory and learning. Diphenhydramine increased the risk of dementia by 54% in one 3,000 patient study followed for seven years. Overdosing on diphenhydramine (Benadryl) can also lead to more serious side effects like severe confusion, seizures, low blood pressure, involuntary muscle spasms, hallucinations (seeing things that aren't there), and heart rhythm problems. In fact, the FDA released a warning to avoid high doses of diphenhydramine.Sep 14, 2022 · Benadryl helps reduce the effects of natural chemicals in the body called histamines. It is used to treat the side effects of an allergic reaction, including: Benadryl can be taken to relieve the symptoms of hayfever (seasonal allergies) and motion sickness. It can also be taken to induce sleep and treat certain symptoms of Parkinson's disease. skin rash. swollen joints. stomach discomfort, upset or pain. tender swollen glands in neck. tremor. unusual excitement, nervousness, restlessness, or irritability. vomiting. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.Jun 15, 2016 · IV administration of 50 mg of DPH resulted in immediate improvement of tremor, rigidity, tachycardia, and eye versions. The patient was started on oral DPH 50 mg 4 times a day and the dose was reduced by 25% every 3 days. Oral clonidine 0.1 mg 3 times a day and a weekly 0.1 mg transdermal patch was added to mitigate sympathetic side effects. Nov 24, 2022 · But it has quite a long list of possible side effects. In fact, the Canadian Society of Allergy and Clinical Immunology has given serious warnings about them, even for people. The organization issued a 2019 position statement about Benadryl. They advised against the drug because of the high risk of side effects and overdose. They said the drug ... Aug 1, 2023 · What are the side effects of Benadryl ... Diphenhydramine is only for short-term use until your symptoms clear up. ... (such as a long car ride, airplane or boat travel, amusement park rides, etc ... Extrapyramidal side effects (EPS), commonly referred to as drug-induced movement disorders are among the most common adverse drug effects patients experience from dopamine-receptor blocking agents. It was first described in 1952 after chlorpromazine-induced symptoms resembling Parkinson disease.[1] A variety of movement phenotypes has since been described along the EPS spectrum, including ...May 25, 2023 · Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Not able to pass urine or change in how much urine is passed. A very bad skin reaction ( Stevens-Johnson syndrome / toxic epidermal necrolysis) may happen. Side effects of antihistamines that make you drowsy can include: sleepiness (drowsiness) and reduced co-ordination, reaction speed and judgement – do not drive or use machinery after taking these antihistamines. dry mouth. blurred vision. difficulty peeing. Side effects of non-drowsy antihistamines can include: headache. Official answer. Diphenhydramine can be used as a short-term sleep aid to help ease occasional sleep problems. Older adults, children under age 16 and pregnant women should avoid taking diphenhydramine, as the risks to these groups may outweigh the benefits. Diphenhydramine should not be taken as a treatment for chronic insomnia. Long-term use may also lead to harmful side effects. The inability to fall or stay asleep can have a significant, negative impact on your mood, productivity, and overall health. Insomnia can also ...Benadryl can cause some children to be hyperactive. OTC cough and cold medicine should not be given to children under the age of 4. Research has shown that these products do not work in children younger than 6 years old and can have serious side effects.Official answer. Diphenhydramine can be used as a short-term sleep aid to help ease occasional sleep problems. Older adults, children under age 16 and pregnant women should avoid taking diphenhydramine, as the risks to these groups may outweigh the benefits. Diphenhydramine should not be taken as a treatment for chronic insomnia.Side effects of antihistamines that make you drowsy can include: sleepiness (drowsiness) and reduced co-ordination, reaction speed and judgement – do not drive or use machinery after taking these antihistamines. dry mouth. blurred vision. difficulty peeing. Side effects of non-drowsy antihistamines can include: headache. Benadryl may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Drinking alcohol can increase certain side effects of diphenhydramine. Ask a doctor or pharmacist before using any other cold, cough, allergy, or sleep medicine.Jul 7, 2022 · Advertisement constipation. blurred vision. memory problems and dementia (especially in seniors) anxiety. dependence. What are the side effects of taking Benadryl every night? SIDE EFFECTS: Drowsiness, dizziness, constipation, stomach upset, blurred vision, or dry mouth/nose/throat may occur. If any of these effects persist or worsen, tell your doctor or pharmacistRead More → Yeah, look at r/dph.Datura is even worse. It's like dph, but way more likely to kill you or make you go blind. Shadow people and spiders and having full conversations with people who don't exist usually only happens in the 400+ category. Between 150mg and there, it's usually just having to piss but being unable to, dysphoria/fear, be May 19, 2022 · Yes, certain side effects are possible after using Benadryl long term. For example, long-term use of Benadryl may cause: an increased risk of dementia; withdrawal symptoms after the drug is stopped* However, keep in mind that doctors typically don’t recommend taking Benadryl as a long-term treatment. Jun 14, 2023 · The symptoms you have noticed are very likely the result of long-term heavy antihistamine use. Antihistamines tend to dry up the nose, which is why they are so effective in humans with allergic rhinitis, but the way they do that is by making the secretions thicker. In dogs, we are not worried much about a runny nose, but we are concerned about ... Common Benadryl (diphenhydramine) side effects include drowsiness, dizziness, and blurry vision. Dry mouth and constipation are common, as well. Serious Benadryl side effects include a greater risk of falls — especially if you are an older adult — and potential long-term memory problems.One Benadryl per night seems to be enough to keep the ears dry & the resulting nausea at bay. I must admit that I'm not sure this is still even a problem for me. The last time I stopped to see if I still needed it was about 2 years ago. After 3 days, the dizziness/nausea/inner ear issues came back, so I promptly started taking the nightly ...• Common side effects of montelukast include upper respiratory infection, fever, headache, sore throat, cough, stomach pain, diarrhea, earache or ear infection, flu, runny nose, and sinus infection.Dec 1, 2022 · Section snippets Sedation. The sedation associated with diphenhydramine is one of the most acknowledged effects of this medication. Indeed, it is frequently used as a medication to treat insomnia. 3 The sedative effect of diphenhydramine is related to its easy penetration of the blood-brain barrier. 4 In the brain, diphenhydramine interferes with H 1 receptors, which causes drowsiness and ... Common Benadryl (diphenhydramine) side effects include drowsiness, dizziness, and blurry vision. Dry mouth and constipation are common, as well. Serious Benadryl side effects include a greater risk of falls — especially if you are an older adult — and potential long-term memory problems.Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Not able to pass urine or change in how much urine is passed. A very bad skin reaction ( Stevens-Johnson syndrome / toxic epidermal necrolysis) may happen.A 2017 study revealed that 10% of adults aged 18-45 use OTC sleep aids while 17.5% of people 65 years and older do. Most over-the-counter options are considered safe when used occasionally—as long as the medication is compatible with any medical conditions you have and other medications you take. But when taken night after night, trouble can ...A 2017 study revealed that 10% of adults aged 18-45 use OTC sleep aids while 17.5% of people 65 years and older do. Most over-the-counter options are considered safe when used occasionally—as long as the medication is compatible with any medical conditions you have and other medications you take. But when taken night after night, trouble can ...Jun 15, 2016 · IV administration of 50 mg of DPH resulted in immediate improvement of tremor, rigidity, tachycardia, and eye versions. The patient was started on oral DPH 50 mg 4 times a day and the dose was reduced by 25% every 3 days. Oral clonidine 0.1 mg 3 times a day and a weekly 0.1 mg transdermal patch was added to mitigate sympathetic side effects. Taking an over-the-counter sleep aid with diphenhydramine once in a while is generally not going to cause problems, other than a possible hangover the next day. Older people, however, can get confused when taking diphenhydramine because it also blocks a brain chemical called acetylcholine, which plays a big role in attention and short-term memory.May 7, 2021 · There is evidence that the use of diphenhydramine among older adults or the elderly may result in serious side effects. This holds true esp. if you are older than age 65. The older a person becomes, the greater the risk of adverse effects. Benadryl is listed as potentially Inappropriate Medication in Older Adults ( also known as Beers criteria) Jun 14, 2023 · The symptoms you have noticed are very likely the result of long-term heavy antihistamine use. Antihistamines tend to dry up the nose, which is why they are so effective in humans with allergic rhinitis, but the way they do that is by making the secretions thicker. In dogs, we are not worried much about a runny nose, but we are concerned about ... But it has quite a long list of possible side effects. In fact, the Canadian Society of Allergy and Clinical Immunology has given serious warnings about them, even for people. The organization issued a 2019 position statement about Benadryl. They advised against the drug because of the high risk of side effects and overdose. They said the drug ...Yeah, look at r/dph.Datura is even worse. It's like dph, but way more likely to kill you or make you go blind. Shadow people and spiders and having full conversations with people who don't exist usually only happens in the 400+ category. Between 150mg and there, it's usually just having to piss but being unable to, dysphoria/fear, be Benadryl may cause serious side effects including: pounding heartbeats or fluttering in your chest, painful or difficult urination, little or no urination, confusion, lightheadedness, tightness in your neck or jaw, and. uncontrollable movements of your tongue. Get medical help right away, if you have any of the symptoms listed above.What are the side effects of Benadryl ... Diphenhydramine is only for short-term use until your symptoms clear up. ... (such as a long car ride, airplane or boat travel, amusement park rides, etc ...and readily penetrates the blood-brain-barrier. Thus side effects such as grogginess, drowsiness, and memory loss are common. Diphenhydramine is also used for motion sickness and extrapyramidal symptoms in Parkinson’s disease patients. Potential harm to the brain: Long-term anticholinergic use has been associated with increasedDiphenhydramine, which is available as an over-the-counter medication, is a first-generation antihistamine that is used in a variety of conditions to treat and prevent dystonias, insomnia, pruritis, urticaria, vertigo, and motion sickness. It also possesses local anesthetic properties for those patients who have allergies to other, more commonly used local anesthetics; however, this is an off ...While there are cases of misuse and abuse, withdrawal symptoms from Benadryl are rare, even with long term use. Nevertheless, Benadryl has strong anticholinergic effects, and there have been reports of 'anticholinergic withdrawal' in some individuals taking Benadryl for extended periods of time. Potential symptoms include:Benadryl can cause some children to be hyperactive. OTC cough and cold medicine should not be given to children under the age of 4. Research has shown that these products do not work in children younger than 6 years old and can have serious side effects.Anxiety. Asthma. Car Sickness. Insomnia. Motion sickness. Reactions to Vaccines. Because one of the common side effect of Benadryl in dogs is drowsiness, your vet may use it to alleviate dog anxiety, particularly associated with traveling and motion sickness that may occur during plane rides or car trips.

Benadryl can cause some children to be hyperactive. OTC cough and cold medicine should not be given to children under the age of 4. Research has shown that these products do not work in children younger than 6 years old and can have serious side effects.. Nearest jimmy john

benadryl side effects long term

Common Benadryl (diphenhydramine) side effects include drowsiness, dizziness, and blurry vision. Dry mouth and constipation are common, as well. Serious Benadryl side effects include a greater risk of falls — especially if you are an older adult — and potential long-term memory problems.Long term use of some antihistamines may increase your risk of dementia. Diphenhydramine (Benadryl®) blocks the effects of a neurotransmitter called acetylcholine. This neurotransmitter is vital for memory and learning. Diphenhydramine increased the risk of dementia by 54% in one 3,000 patient study followed for seven years. Yeah, look at r/dph.Datura is even worse. It's like dph, but way more likely to kill you or make you go blind. Shadow people and spiders and having full conversations with people who don't exist usually only happens in the 400+ category. Between 150mg and there, it's usually just having to piss but being unable to, dysphoria/fear, be Oct 3, 2022 · Adults and children ≥12 years of age receiving conventional or orally disintegrating tablets: Headache, somnolence, fatigue, dry mouth. Fixed combination loratadine (the active ingredient contained in Claritin) pseudoephedrine sulfate preparations: Insomnia, dry mouth, headache, somnolence, nervousness, dizziness, fatigue. It can sometimes cause a decrease in memory, confusion, and thinking issues. These side effects are more common in elders. In addition, taking Benadryl long-term might increase the risk of dementia. People aged> 65 who took medications such as Benadryl daily for over three years had an increased risk of dementia.Jun 8, 2022 · Sleep aids: The options. Sleep aids available without a prescription are widely available. Common choices and the potential side effects include: Diphenhydramine (Benadryl). Diphenhydramine is a sedating antihistamine. Side effects might include daytime drowsiness, dry mouth, constipation and urinary retention. Doxylamine (Unisom). May 25, 2023 · Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Not able to pass urine or change in how much urine is passed. A very bad skin reaction ( Stevens-Johnson syndrome / toxic epidermal necrolysis) may happen. Diphenhydramine or : Benadryl (diphenhydramine) may cause sedation the next day (due to its long half-life), decreased alertness, diminished cognitive function, delirium, ... Read More. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help. 5k views Reviewed >2 years ago. and readily penetrates the blood-brain-barrier. Thus side effects such as grogginess, drowsiness, and memory loss are common. Diphenhydramine is also used for motion sickness and extrapyramidal symptoms in Parkinson’s disease patients. Potential harm to the brain: Long-term anticholinergic use has been associated with increased and readily penetrates the blood-brain-barrier. Thus side effects such as grogginess, drowsiness, and memory loss are common. Diphenhydramine is also used for motion sickness and extrapyramidal symptoms in Parkinson’s disease patients. Potential harm to the brain: Long-term anticholinergic use has been associated with increasedHives. Swelling and inflammation. Redness. Runny nose and eyes. Coughing. Sneezing. Anaphylactic reaction. One of the side effects of Benadryl is drowsiness, which can help to calm anxious dogs ...Side effects of antihistamines that make you drowsy can include: sleepiness (drowsiness) and reduced co-ordination, reaction speed and judgement – do not drive or use machinery after taking these antihistamines. dry mouth. blurred vision. difficulty peeing. Side effects of non-drowsy antihistamines can include: headache. and readily penetrates the blood-brain-barrier. Thus side effects such as grogginess, drowsiness, and memory loss are common. Diphenhydramine is also used for motion sickness and extrapyramidal symptoms in Parkinson’s disease patients. Potential harm to the brain: Long-term anticholinergic use has been associated with increased Adults and children ≥12 years of age receiving conventional or orally disintegrating tablets: Headache, somnolence, fatigue, dry mouth. Fixed combination loratadine (the active ingredient contained in Claritin) pseudoephedrine sulfate preparations: Insomnia, dry mouth, headache, somnolence, nervousness, dizziness, fatigue.Long-Term Side Effects of Diphenhydramine Abuse. Continued diphenhydramine use can cause long-term adverse side effects that result in permanent damage. Not only will prolonged use cause harm, but it can lead to other aspects such as dependence on the medication. Common long-term side effects of prolonged diphenhydramine use include: Dependence. Benadryl may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Drinking alcohol can increase certain side effects of diphenhydramine. Ask a doctor or pharmacist before using any other cold, cough, allergy, or sleep medicine.Overdosing on diphenhydramine (Benadryl) can also lead to more serious side effects like severe confusion, seizures, low blood pressure, involuntary muscle spasms, hallucinations (seeing things that aren't there), and heart rhythm problems. In fact, the FDA released a warning to avoid high doses of diphenhydramine.Long term use of some antihistamines may increase your risk of dementia. Diphenhydramine (Benadryl®) blocks the effects of a neurotransmitter called acetylcholine. This neurotransmitter is vital for memory and learning. Diphenhydramine increased the risk of dementia by 54% in one 3,000 patient study followed for seven years. Benadryl can cause some children to be hyperactive. OTC cough and cold medicine should not be given to children under the age of 4. Research has shown that these products do not work in children younger than 6 years old and can have serious side effects.Benadryl is a brand of diphenhydramine. As far as long term effects. Look up Benadryl or diphenhydramine and dementia on google then come back to me. I am a 10 year 50mg daily user of diphenhydramine and am slowly stopping this stuff. The past few weeks I have been reducing to 1/2. Trust me, take this for long term and you increase risk of ....

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